In a first of a kind event, a group of scientists from Stanford University and Scripps Research recorded the assembly of ribosomes in real-time. Ribosomes are instrumental in making proteins in the cells. The study reveals the entire procedure of the assembly. The scientists can know how the ribonucleic acid chaperoned by ribosomal proteins to form a key component of ribosomes.
The recent findings proved the initial belief about ribosomes were incorrect. Previously, scientists were predicting that the ribosomes assembled in a stepwise tightly controlled process.
James R. Williamson, a professor in the Department of Integrative Structural & Computational Biology, revealed that the recent findings would completely change the initial claims. The researchers found a far more chaotic process in comparison to the initial request. While giving an example to understand the importance of the development, he stated that the process is like a trading pit on Wall Street.
The study conducted by a collaboration of Williamson’s lab and the lab of Joseph Puglisi. Joseph Puglisi is a working professor at Stanford University. The new findings will change the basics of cell biology. The results will also help in the development of medicines.
Currently, antibiotics use inhibiting bacterial ribosomes. But after the new findings, the antibiotics will target specific bacterial ribosomes. As a result, the side effects of the medicines will be significantly reduced.
The new research will also help the biologists to study RNA molecules. There are millions of RNAs are active inside a cell at any given moment.
The research team used an advanced version of imaging technology called zero-mode waveguide single-molecule fluorescence microscopy. The technology helped the scientists to track RNAs and proteins on a real-time basis.
Ribosomes are the primary source of life and found in most organisms in the modern world. Ribosomes are made up of proteins and RNA and believed to exist since the beginning of life on earth.